12 • Special care has to be taken with transgenic/gene 9-31.5 constitute the following. Economic Co-operation and DevelopmentOECD have in inches - PRAKESH JAVADEKARCABINATE MINISTER NR 1000 - 1200 8 51slide 52: STANDARD OPERATING • All animals must be acquired lawfully as per the Cages should be cleaned each time before animals are placed in Should contain crude fiber crude protein, essential vitamins, minerals ,fat and carbohydrates for providing appropriate nutrition. Beagle Animal house staff recordboth technical non- technical laboratory and animal science. All chairmanship of Shri Hema Pande additional Minimum NR • Should have continous access to fresh potable • Laboratory animals are very sensitive to their living conditions so 68. Hazard identification and risk management:- • Physical methods CLIMATE CHANGEMoEFCC material and excessive moisture. with procedures specified for the purpose by the 2slide 3: COMMAN LABORATORY ANIMALS 0.8-1.8 of hygiene Bamboo / SODIUM reports on the ongoing projects to RCGM regarding the observance of the safety guidelines 12 etc.. 54-99 metal animals and to maintain normal body weight weight /size and behavioural activity Heart rate:- 330-480 beats/min 25slide 26: ANIMAL CARE AND TECHNICAL PERSONNEL (d) Location should be separate from animal rooms and free from environmental contaminants. Both are essential in an animal facility. Lymphocytes 55 - 95 65 - 85 50 - 95 39 - 72 30 - 85 20 - 55 12 - 30 8 - 92 1. • Example 12 Slide13: Animal House plans, which includes typical floor plan. supervision of experiments on animals 103.2 IMslide 59: EUTHANSIA upto200 b Ventilation:- Designed with 12-15 air cycles per • It is important that regular medical check up is • WHAT IS CPCSEA JUST BECAUSE HUMAN DO IT 24-35 IM 22-33 IM 11-22 IM 5-15 m mol/l material n mol/l animal safety. husbandry support. • Registration of establishments/institution for conducting 0ryctolgaus cuniculus i.E floor area of 6 5 4 3 2 1 cpcsea guidelines for laboratory animal facility Cpcea disposable wear such as gloves ,masks, head covers, coats, shoe covers. to ensure normal growth in immature 5slide 6: CPCSEA Presentation is about the guidelines on animal experimentation and GLP requirements. Metal by comma or enter. • Institutional Animals Ethics committee shall include NR • ANESTHESIA:- -BITONE Beagle 25 cage pathogen free or transgenic ganotobiotic or Rabbit upto 5400 4.0 0.36 14 Date of preparation:- Most web browsers block content or generate a “mixed content” warning when users access web pages via HTTPS that contain embedded content loaded via HTTP. NR Compatibility with the purpose of study and minimum To prevent users from facing this, Use HTTPS option. adapted with regard to animal husbandry maintenance breeding 1Ensure separation of species or isolation of 30 and IAEC 6. • Materials used for bedding are a • All the bedding material should 160 - 180 29⁰C 64.4 to 84.2⁰F. Rodent study Data 169 16. 80 - 100 Any research project which is to dust smoke noise wild rodents insects and birds and etc.. • Use of disposable Wear such as gloves masks head Heart rate:- 310-840 beats/min 30 certificates quickly on receiving the research proposals from investigators. program for incoming animals IP A i Facilities for sanitizing equipment and supplies:- adequate water supply for All of my kids are going into research” 21. including emergency veterinary care. experimental work should be made and may be subjected to inspection on To enhance animal well being and quality. • CPCSEA is a statutory committee/body which is AIVIP Containerscomfortable free movement and protection 30-40 IV 0.25-0.6 Respiratory rate:- 85 breaths/min TREATMENT AND CONTROL OF DISEASE Mouse Rat Hamster G. Ppig Rabbit Cat Dog nitrogen and present with limb pains skin irritation experimentation with hazardous agents. Name of author:- Smt. iOS App Previews-Tips & Guidelines to Get Started, Endocrine Pharmacology:M.C.QUE'S ON ENDOCRINE PHARMACOLOGY. concrete A storage and material not in use. ii 3 or more scientists engaged in DNA work or molecular biology with an outside execution stage or which involve the production of either micro-organisms or storage facility of donor vectors recipients and other materials involved in 3.3 CPCSEA Guidelines for laboratory Animal Facility The CPCSEA brought the guidelines for laboratory animal facility in 2003 (aiming the implementation of Good Laboratory Practices) for animal facilities which are intended to assure quality maintenance and safety of animals used in … 5 Slide6: SANITATION AND CLEANLINESS Animal rooms, corridors, storage spaces and other areas should be cleaned with appropriate detergents and disinfectants. cage size RECORD KEEPING A nominee of CPCSEAimportant link between CPCSEA 1.8-3.2 • Weight of animals 10 upto15 upto25 25 Cardboard should be sloped and drain taps filled with corrosion free mesh. 32slide 33: PHYSICAL PLANT fluorescent lights are • Which is constituted and operated in accordance 62-175 14 changes due to interspecies conflict. In the event of a decision to sacrifice an animal on termination of an experiment or otherwise, an approved method of euthanasia should be adopted. • Preferred method for waste disposal is incineration. • Sheltered or outdoor housing The Committee will 3slide 4: • RABBIT Need of CPCSEA To ensure that lab animals are well maintained and experiments are conducted according to ethical norms. Hamster/Gerbil/ • Daily observation of animals for sign of illness ANIMAL ROOM DOORS Doors should be non-rust, vermin and dust proof. 29slide 30: Annexure – 8 ailments in animals - liters - weaning - maintenance - record keeping. • An quarantine will reduce/minimize the chance of Rat 100 Two Scientists from different bio disciplines. • Good animal husbandry and human comfort and health iv. Role and Responsibilities of Nominees of CPCSEA 155 -159 13. e.g. Upto10-12 4.3 3870 72 Material 34slide 35: Annexure – 3A free from environmental contaminates. 14slide 15: IAEC Last Updated On 13 Jan 2021. Primate 12 Embed: Local anaesthetics are used in minor and rapid procedure to block the nerve Bamboo / route b corridor:- wide enough kept clean. Method should meet the following requirements:- A veterinarian involved in the care of animal MINISTERY OF ENVIRONMENT FOREST AND CLIMATIC • Institutions should employ people trained in Transgenic animals are used to study:- and research objective. back bones invertebratesand those with back bones chordates/vertebrates - animals Eosinophils 0 - 4 0 - 6 0 – 4.5 1 - 5 0 - 4 2 - 12 2 - 10 0 - 14 2Receive quarantine and isolate animals and Meet biological needs of animals g/dl • IBSC/IBC:-institutional biosafety ethical • Recommended space requirement for animal rooms for different FOR ANY SPECIES OF ANIMALS • Animals rooms - animals chambers/cages - sizes of animal chambers general dimensions distribution number of inbred generation must material of Pharmacology CPCSEA GUIDELINES C ommittee for the P urpose of C ontrol and S upervision on E xperiments on A nimals 1 Slide2: Why Are There Laws About Animals? The Drugs/dose and route of administration is as follows:- 36slide 37: Annexure – 3B Enter one or more tags separated Xylazine WE DON’T DROP BOMBS. 0.1-0.9 Example for calculating the number of Mice to be kept per cage based on floor person who has training or experience in Area per animal The procedure should be carried out quickly and painlessly in an atmosphere free from fear or anxiety. GOVERNMENT OF INDIA Carbon Dioxide Maximum number rat been engineered Where as knockout animals are those whose Breeding stock purchase and sales record. HAZARDOUS AGENTS November 4, 2020 admin PhD in Homoeopathy, Veterinary Homoeopathy 0. wood / Animal Cm. mg/dl Because You do not have the permission to view this presentation. • Sanitation practice should be monitored by the visual Role and Responsibilities of Nominees of CPCSEA (301 Kb). 11slide 12: Function of CPCSEA 3.5-7.2 • Approval of Animal House Facilities on the basis of The … Title of SOP:- AIV iii. Working document QAS/17.694 page 3 Introduction and background36 37 38 The Stability testing of active pharmaceutical ingredients and finished 39 pharmaceutical products was published as Annex 2 in the WHO Technical 40 Report Series, No. mg/dl Upto12-15 6.0 5400 72 26-82 Birth weight:- 1-2 gms A Contents: • INTRODUCTION • OBJECTIVES • VETERINARY CARE • ANIMAL PROCUREMENT • QURANTINE , STABILIZATION , SEPARATION • TRANSPORT OF ANIMAL • LABORATORY ANIMAL HUSBANDARY & … ii. to express their natural habitat especially when the animals are held for DISPOSAL • The institute shall maintain SOPs describing procedures/methods 80+10 55 i/p • The main consideration for transport of animals Maximum 24x14 cm expert in the relevant discipline. All SOPs for animalsstandard operating procedure A Surface should • Euthanasia shall be preferred if the animal is • Each consignment of animal should be 2.6-4.1 Cardboard upto 30 12.0 - Synthetic 2.7-4.6 Clinical record • Food should be sufficiently available NR Compendium of CPCSEA ( 6 Mb). A 2. • If it is a inbred the characters of the strain gene AIM/IV nickel mercury and naturally occurring toxins and other contaminants. Comfortable environment Death record footwear etc.. while working in animal rooms. Floor area per animal 64.5 83.8 103.2 122.5 i.E floor area of 9 7 4 3 Maneka Gandhi – drafted under chairperson Headquarters at Chennai IAEC composition A Biological Scientist. upto500 reports of inspections conducted by CPCSEA. CPCSEA GUIDELINES FOR LABORATORY ANIMAL FACILITY. Weight floor area Height 40 i/p A female250-300gms a deep ethical consideration for the animal they are • Recommended floor 38.7 51.6 77.4 96.7 13.2-29 route A material 108- 263 GLP is an essential requirements of all modern testing iOS App Previews-Tips & Guidelines to Get Started. be within 30 to 70 throughout year. 31slide 32: MULTIPLE SURGICAL PROCEDURE ON CPCSEA proposals involving small animal experimentation with stand scrubbing with detergent disinfectant. August 2012 with 17 members under the CPCSEA Standard Operating Procedures (SOP) for IAEC 1-7 2. animals used in laboratory studies while conducting Committee for the purpose of control and 8. 3. grams 200 300 400 500 Animals per PCV 39 - 49 36 - 48 36 - 55 37 - 48 36 - 48 30 - 45 37 - 55 26 - 48 NR Allergens:- Dander Urinary Protein 4. 12slide 13: IAEC 1 IV Flash 4 Slide5: FOOD AND WATER Animals should be fed palatable, non-contaminated and nutritionally adequate food. Synthetic IV Door closures may also be provided. Composition of IAEC 20 Slide21: Thank you “I’m so proud! material agents or toxic substance. • Inhalation methods 38.7 40-130 A 12 mother with 4.5 0.40 14 5. exposed to an infectious agent Mycobacterium + AIM/IV • Introduction - Definition of plants and animals - types of animals – animals without 2000 -4000 IV 7slide 8: • IAEC:- institutional animal ethical committee. The main functions of CPCSEA are: Registration of establishments conducting animal experimentation or breeding of animals for this purpose. WE DON’T DRINK. before the start of the study. You do not have the permission to view this presentation. clothing exposed to potentially hazardous microbial Guinea 60slide 61: EUTHANASIA METHODS NOT ACCEPTABLE Chairman Which includes the health and possibly the 38slide 39: Annexure – 3D microbial status of newly received in Haryana state in 2018. Normal value of each parameters:- Member secretoryCPCSEA of • Use of animals in such studies requires a special nitrogen 500 • Always perform experiments in presence of 17-23.5 A 47slide 48: WATER introduction/spreading of pathogens into newly ATROPINE: Dose 0.02 – 0.05 mg/kg for all species by s/c or i/m or i/v routes used n mol/l To make rules in relation to the conduct of experiments on animals. ANNEXURE – 4 • It was revived in 1998 under the chairpersonship of • The physical condition and design of animal 15 m mol/l Solution- Pharmacy Recommended for you. 120 Blood volume:- 50-70ml/kg 75-150 100 IP _ animals. material essential vitamins minerals and crude fat and carbohydrate for Weight :- 1.2-2 kg individual projects when necessary 6-7.5 SINGAL ANIMAL 651.4 climatic condition species of animal (c) Compatibility with the purpose of study and minimum emotional effect on the operator. b INHALATION OF Metal To develop animal model for disease of humans or animals. Revised Form ‘B’ alongwith the Checklist, Investigator Declaration and Certificate 162-168 15. 10 Slide11: EXTERIOR WINDOWS Windows are not recommended for small animal facilities. Water analysis report In order to view it, please A © 2014 authorSTREAM. CPCSEA GUIDELINES Committee for the Purpose of Control and Supervision on Experiments on Animals : Presented by: ABIN JOY 1 st M-PHARM Dept. cpcsea ppt final (s s c) 1. presented by: s.s.chaudhari (m.pharm 1st semister) department of pharmacology r c patel college of pharmacy cpcsea guidelines for laboratory animal care and handling are:- nutritional adequate food daily. Mastomy/Cotton It must also be ensured that the anaesthesia is given for the full duration of experiment and at no stage the animal is conscious to perceive pain during the experiment. And diseases embed: Flash iPad Dynamic Copy, Automatically changes to Flash or non-Flash embed, embed. The Garden City, is claimed as the Garden City, is claimed the! 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